Synthesis and Characterization of Novel Benzimidazole Derivative as Potent Anthelmintic Agent

Abstract

The Chemistry of Heterocyclic compounds has been an interesting field of study, for a long time. The Benzo fused heterocyclic nucleus Benzimidazole founds an important class for new drug development. 4-((1H-benzimidazol-1-ylimino) methyl) phenol (5d) is the most effective among all derivatives as compared to albendazole standard and showed best anthelmintic potential at 0.1% concentration showed best paralysis time at 4.35±0.10, and death time at 09.33±0.63 respectively as compared to albendazole (Standard).  Finally, it was concluded that all benzimidazole derivatives possess potent anthelmintic activities.