Phytochemical Screening and in Vitro Anti-Plasmodium Falciparum Activity of Alstonia Scholaris

Abstract

Malaria is a major global threat that results in more than 2 million deaths each year. In India, malaria is one of the most important causes of direct or indirect infant, child, and adult mortality. The plant Alstonia scholaris has been used in different systems of traditional medicine for the treatment of diseases. The extract of the plant showed pharmacological activities ranging from anti-malarial to anticancer properties.  The extract was subjected for pharmacological screening and tested against P. falciparum, which exhibited 14 mm zone of inhibition of 200mg/mL.  It can be concluded from the present study that the bark and leaf extracts of A. scholaris potentiate the antiplasmodial activity against P. falciparum